Upcoming NINR-Sponsored Workshop

Workshop on Integrating Cost-Effective Analysis into Clinical Research

National Institute of Nursing Research
National Institutes of Health

Natcher Conference Center
NIH Campus, Building 45
Bethesda, MD
July 17-18, 2008

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Objectives:

The overall objectives of this workshop are to:

Improve the participants understanding of the importance of cost-effectiveness analysis; and
Identify tools to integrate cost-effectiveness analysis into clinical research.

Goals:

Specific goals include:

Discuss current knowledge related to cost-effectiveness analysis;
Strategize next steps for incorporating cost-effectiveness analysis in clinical interventions to provide recommendations that will promote the development of a research agenda.

Background:

Because any single rare disease occurs in a small number of patients (<200,000), the economic impact is surmised to be less than another illness that affects a wider population. However, with over 6,000 rare diseases identified in the United States, this group of disorders may pose a significant societal burden. Rare diseases are often associated with disability, loss of role and employment status, chronic morbidity, and early mortality requiring the extended use of expensive treatment modalities.

New health care technologies and interventions, including interventions for self-management, for rare diseases are emerging. Thus, it will be important to develop the capacity to identify technologies and interventions that maximize health outcomes and optimize the cost-benefit ratio. Rare disease experts such as the 2004 NINR-sponsored working group on "Increasing Opportunities in Clinical Research: Expert Working Group Utilizing Allergic Bronchopulmonary Aspergillosis as a Framework," have recommended increased attention to the economic impact of rare diseases for both the individual and society. Therefore, a research agenda focused on cost-effective analysis (CEA) will be a critical step in shaping future policy initiatives to support the allocation of scarce health resources for the treatment of rare diseases.

Integrating cost effectiveness with evaluation of biobehavioral interventions promotes a research agenda of long standing interest to the NINR.

AGENDA

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July 17, 2008

8:15-9 a.m.	Light Refreshments and Registration
9-9:15 a.m.	Welcome & Opening Remarks Dr. Patricia A. Grady, Director, NINR
9:15-9:30 a.m.	Overview & Purpose of the Workshop Drs. Paul Cotton and Karen Huss
	Challenges in Use of Cost-Effectiveness Analysis Coordinator: Dr. Paul Cotton
9:30-10 a.m.	What is Cost-Effectiveness Analysis and Why is it Important? Patricia Stone, PhD, MPH, RN Columbia University
10-10:30 a.m.	Overview of Cost-Effectiveness Analysis in Clinical Research David Feeny, PhD The Center for Health Research, Kaiser Permanente Northwest, the University of Alberta, and Health Utilities Incorporated
10:30-11 a.m.	Trends and Issues to Applying Cost-Effectiveness Analysis: William Lawrence, MD, MS Healthcare Outcomes Assessment, Agency for Healthcare Research and Quality
11-11:20 a.m.	Break
11:20-11:50 a.m.	Applying Cost-Effectiveness Analysis: The COPE Prevention for Parents of Preterms Bernadette Melnyk, PhD, RN, CPNP/NPP, FAAN, FNAP Arizona State University
11:50 a.m.-12:20 p.m.	Plan for the Best - Prepare for the Worst: Tales from the Data Trenches Barbara Mark, PhD, RD, FAAN University of North Carolina, Chapel Hill
11:55 a.m.-12:30 p.m.	Response and Discussion
12:30-1:45 p.m.	Lunch (on your own)
1:45-2:15 p.m.	Cost-Effectiveness Analysis and the Policy Making Process Kevin Frick, PhD Johns Hopkins University
2:15-3:15 p.m.	Working Groups/Small Group Sessions
3:15-3:30 p.m.	Integration of Working Groups/Small Group Sessions
3:30-4 p.m.	Cost Utility Analysis Mark Roberts, MD, MPP, FACP University of Pittsburgh
	Challenges in Research Design and Measurement Coordinator: Dr. Huss
4-4:30 p.m.	Health Benefit Valuation and Discounting William Lawrence, MD, MS Health Outcomes Assessment Agency for Healthcare Research and Quality
4:30-4:45 p.m.	Break
4:45-5:15 p.m.	Identification of Strategies to Integrate Cost-Effectiveness Analysis into Research Kevin Frick, PhD Johns Hopkins University
5:15-5:45 p.m.	Discussion Summary of Day 1 Patricia Stone, PhD, MPH, RN Columbia University

July 18, 2008

	Challenges in Research Design and Measurement (Continued) Coordinator: Dr. Huss
8:15-9 a.m.	Light Refreshments
9-9:30 a.m.	Measuring Cost and Inflation Over Time Patricia Stone, PhD, MPH, RN Columbia University Kevin Frick, PhD Johns Hopkins University
9:30-9:45 a.m.	Discussion
9:45-10:15 a.m.	Designing Cost-Effectiveness Analysis Clinical Interventions: Methodological Considerations Mark Roberts, MD, MPP, FACP University of Pittsburgh
10:15-11:15 a.m.	Working Groups/Small Group Sessions
11:15-11:30 a.m.	Integration of Working Groups/Small Group Sessions
11:30-11:45 a.m.	Break
11:45 a.m.-12:45 p.m.	Future Directions for Research (30-Minute Panel Discussion) Discussion - All
12:45-1:15 p.m.	Final Questions & Answers

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Logistics

Arrangements: Travel arrangements are your own responsibility, but you should know that three airports serve the Washington, D.C., metropolitan area. Please make your own hotel reservations. Should you decide to extend your stay to take advantage of lower fares, Washington-area attractions are only a short trip away from any of the suggested hotels. Hotel and travel information is listed below.

Visitor Information: Natcher Conference Center is located in Building 45 on the NIH Campus. For a map, general information, and directions to and around the NIH Campus, visit: http://parking.nih.gov/visitor_access_map.htm.

NIH Security: The NIH, like all Federal government facilities, has instituted security measures to ensure the safety of NIH employees, patients, and visitors. The national threat advisory level, determined by the Department of Homeland Security (http://www.whitehouse.gov/homeland/), currently is yellow (elevated).

Perimeter Security: All visitor vehicles, including taxicabs, hotel and airport shuttles, delivery trucks, and vans will be inspected before being allowed on campus. Visitors will be asked to show (1) form of identification (a government-issued photo ID; driver's license; passport; green card, etc.) and to state the purpose of their visit. Be sure to allow extra time for this vehicle inspection procedure.

Building Security: Due to the checking of IDs at the perimeter, employees and visitors will not be required to show their ID again to gain access to the majority of buildings on the NIH campus during the normal business day. Employees and visitors should continue to wear their identification prominently at all times while on campus. Guards will remain at certain buildings to address specific program requirements, such as sensitive research and safety concerns. At building entrances where guards are posted:

Employees must show a DHHS-issued photo ID (for example, your NIH-issued ID badge).
Visitors may be required to log in, wear a visitor's pass, and be escorted by an employee through the buildings.
Visitors may be required to pass through a metal detector and have bags, backpacks, or purses inspected or xrayed as they enter buildings.
Security staff will confiscate any suspicious or potentially dangerous materials. U.S. code prohibits bringing any dangerous weapons onto Federal property, including anything with a blade longer than 2.5 inches. Meeting participants may want to leave extra bags or personal materials at their hotel to minimize the time needed for inspection.

Weekday Campus Access: Visitors, including patients, contractors, vendors, and delivery persons, must use the following entrances (see the Visitor Map at http://parking.nih.gov/visitor_access_map.htm):

Rockville Pike at South Drive (Metro) - Open 24 hours for inbound and outbound traffic on weekdays.
Old Georgetown Road at Center Drive - This entrance is primarily for commercial vehicles and visitors. It is open weekdays from 5 a.m. to 2 p.m. for INBOUND traffic only; from 2 p.m. to 7 p.m. for both INBOUND and OUTBOUND traffic; and it is closed to ALL traffic from 7 p.m. to 5 a.m.

Hotel Reservations: The following hotels provide lodging that is easily accessible by either Metro, shuttle bus, or within a short walk of the NIH campus:

Bethesda Marriott Hotel
5151 Pooks Hill Road
Bethesda, MD 20814
Phone: 301-897-9400
Toll-Free: 800-228-9290
Fax: 301-897-0192

Bethesda North Marriott Hotel & Conference Center
5701 Marinelli Road
North Bethesda, MD
Phone: 301-822-9200
Toll-Free: 800-228-9290
Fax: 301-822-9201

Hilton Executive Conference Center
1750 Rockville Pike
Rockville, MD 20852
Phone: 301-468-1100
Toll-Free: 1-800-HILTONS
Fax: 301-468-0308

Hyatt Regency Bethesda
One Bethesda Metro Center
Bethesda, MD 20814
Phone: 301-657-1234
Toll-Free: 800-633-7313
Fax: 301-657-6453

DoubleTree Hotel
8120 Wisconsin Avenue
Bethesda, MD 20814
Phone: 301-652-2000
Toll-Free: 800-222-TREE
Fax: 301-652-4525

American Inn of Bethesda
8130 Wisconsin Avenue
Bethesda, MD 20814
Phone: 301-656-9300
Toll-Free: 800-232-7081
Fax: 301-656-2907

Residence Inn
7335 Wisconsin Avenue
Bethesda, MD 20814
Phone: 301-718-0200
Toll-Free: 800-228-9290
Fax: 301-718-0679

Rockville Ramada Inn
1775 Rockville Pike
Rockville, MD 20852
Phone: 301-881-2300
Toll-Free: 800-272-6232
Fax: 301-881-9047

Metro: The Metro system is clean, reliable, and safe. It operates from 5 a.m. to midnight on Monday through Thursday; 5 a.m. to 3 a.m. on Fridays; 7 a.m. to 3 a.m. on Saturdays; and 7 a.m. to midnight on Sundays. Each passenger must purchase a fare card to travel in the system. Instructions for purchasing fare cards are posted on the vending machines in each station. Each Metro car features a complete color-coded map of the system. Station attendants on duty at each station can provide additional information on request. From Ronald Reagan Washington National Airport, a cost-effective way to travel to the hotel is by using the Metrorail system. A map of the system is available at http://www.wmata.com/metrorail/systemmap.cfm. The hotels listed above are within walking distance of a Metro stop.

From the Airport station, take the Yellow Line toward Mt. Vernon Square. At the Gallery Place/Chinatown station, transfer to the Red Line toward Shady Grove. If you are staying at the Holiday Inn or the American Inn, exit at the Medical Center stop. If you are staying at the Hyatt Regency Bethesda, exit at the Bethesda stop.

Bethesda Station - Hyatt Regency, Residence Inn
Medical Center Station - American Inn, Holiday Inn, Bethesda Marriott (call for hotel shuttle)
White Flint Station - Bethesda Marriott North Hotel and Conference Center
Twinbrook - Hilton and Ramada

SuperShuttle: SuperShuttle offers service to most hotels from Ronald Reagan Washington National Airport. The shuttle leaves on an as-needed basis between the hours of 5:30 a.m. and 11 p.m. During other times, arrangements for a shuttle can be made by calling 800-258-3826 from the airport, or visit their web site at http://supershuttle.com.

Taxi: The taxi fare is approximately $45-$50 from Ronald Reagan Washington National Airport; approximately $55-$65 from Washington Dulles International Airport; and approximately $55-$65 from Baltimore/Washington International Thurgood Marshall Airport. Fares may differ during peak travel hours.

Parking: Parking on the NIH Campus is limited and is $12 per day for visitors.

Conference Registration