Below are links to essential information for particular aspects of the application process.

Several elements of essential information are enhanced by Decision Trees developed by other Institutes and Centers at NIH to help investigators learn how reviewers determine an applications compliance with human subject protection requirements, data and safety monitoring plans/boards and gender/minority/children inclusion requirements. These decision trees are generally applicable to research supported by any NIH Institute.

Note: Some files listed here are Word Documents, requiring Microsoft Word viewer to view them. Microsoft Word viewer can be downloaded here.

Federal-wide Assurance
Policy on Reporting Race and Ethnicity Data

Policy on Reporting DUNS Number on Each Competing Application

Information from the NIH Office of Human Subjects Research

Required Education in the Protection of Human Subjects in Research

  • At least two online courses are available to provide this training. One is Learning About Clinical Trials and the other is PRIM&R Investigator 101 CD-ROM for Training in Human Subjects Protection

NIH Policy for Data and Safety Monitoring

Procedures for Applications Requesting Direct Costs of $500,000 or More in Any Year

Modular Grants

Information on Certificates of Confidentiality is available on the NIH web site at the CoC Kiosk.