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Themes: End-of-Life and Palliative Care

End of Life and Palliative Care: The Science of Compassion

End-of-life and palliative care science develops strategies to prevent, reduce, or comfort the symptoms of advanced illness. It includes management of pain and other symptoms and emotional, social, spiritual and informed decision-making support. Interventions address supportive, palliative, and hospice needs across a continuum of services in coordination with individuals, families and their health care teams. Science advances from NINR end-of-life and palliative care research include:

  • Clinician-patient discussions about preferences for life sustaining treatments could reduce unwanted treatments at the end-of-life. View PubMed Abstract
  • Improving communication and providing decision support helps parents making difficult decisions regarding the care of their children who have life threatening illnesses. View PubMed Abstract
  • Increasing per diem rates for individuals who require complex palliative treatments and removing Medicare hospice benefit limitations on concurrent care may enable hospices to expand enrollment. View PubMed Abstract
  • Residents from nursing homes in rural areas had higher rates of in-hospital deaths and less hospice use than those in urban areas, highlighting differences in end-of-life care based on geographic location. View PubMed Abstract

Selected Funding Opportunities

  • PAR-13-289: Building Evidence: Effective Palliative End of Life Care Interventions (R01). Open September 8, 2013-June 10, 2016
  • PA-13-354 and PA-13-355: Advancing the Science of Geriatric Palliative Care (R01, R21). Open January 5, 2014-January 8, 2017
  • RFA-NR-14-003: The Palliative Care Research Cooperative (PCRC): Enhancing Sustainability and Building the Science of Palliative Care (R01). Open December 4, 2013-March 20, 2014 (Letter of Intent Due: February 20, 2014; Application Due Date: March 20, 2014)

Please see the NINR Funding Opportunities page for a complete list of NINR co-sponsored funding opportunities.

NINR Contacts

Chief - Office of End-of-Life and Palliative Care Research

Dr. Jeri Miller

Extramural Programs contacts in End-of-Life and Palliative Care:

Dr. Lynn Adams
Dr. Karen Kehl


For more information on end-of-life and palliative care, visit the following pages:


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