Identification of a Potential Blood-based Biomarker for Diagnosing Mild Traumatic Brain Injuries
Researchers at NINR have shown that a protein known as GFAP could be used as a blood-based biomarker for detecting mild traumatic brain injuries (TBIs). Annually, millions of individuals experience TBIs through falls, sports injuries, motor vehicle accidents, and many other causes. Currently, brain imaging is regularly used in the medical community to detect and assess mild TBIs. However, the availability of a blood-based test to detect milder forms of brain injury could allow accurate, less expensive, and faster treatment for these patients. These new findings with GFAP could lead to the development of a much-needed blood test to improve the ability of clinicians to quickly diagnose and treat mild TBIs as an alternative or in combination with brain imaging.
Gill J, Latour L, Diaz-Arrastia R, Motamedi V, Turtzo C, Shahim P, Mondello S, DeVoto C, Veras E, Hanlon D, Song L, Jeromin A. Glial fibrillary acidic protein elevations relate to neuroimaging abnormalities after mild TBI. Neurology. 2018 Oct 9; 91(15):e1385-e1389. doi: 10.1212/WNL.0000000000006321. Epub 2018 Sep 12 PMID:30209234